Photoreactive aminoacids for studying protein interactions

Photoreactive aminoacids for studying protein interactions has found out with several advantages over other conventional techniques used today. Coimmunoprecipitation GST pull downs are used to study protein-protein interactions in a lysed cell sample. Photoreactive amino acids can be incorporated by using cells own protein synthesis machinery can be used to study these interactions within live cells.Photo-leucinr and Photo methionine is widely used for this assay.

Super Drugs

Drug Resistance is considered as the major problem in drug discovery.Most bacteria become resistant to drugs on continous exporsure.Super drugs are now designed which aims to target on multiple gene so that resistance can be minimised.Novel drugs targeting ribosomes and lytic phages specific to bacteria also proved to prevant drug resistant bacterial strains.this will be surely a good news for this drug discoverers.

Minimising Cross Reaction

ELISA,ImmunoPCR etc are greatly affected by the problem of cross reactivitywhich may leads to false results.This phenomena is refered to as interference.Candor Bioscience~s Low Cross Buffer had shown to minimise the cross reactivity.This buffer allows high affinity binding while low and medium affinity binding is blocked.

This buffer will be great help for immunologist to prevant false negatives and positives